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Updated: Jun 25, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Case report: histologic study of a human epiphyseal transplant at 3 years after implantation
J Sales de Gauzy1, F Accadbled, A Gomez Brouchet
1Department of Pediatric Orthopaedic Surgery, Hôpital des Enfants, Toulouse, France.
Abstract:
A 5-year-old boy underwent surgical excision of a Ewing's sarcoma of the proximal femur. Reconstruction was performed using an ipsilateral vascularized epiphyseal transplant and a femoral allograft. Local recurrence of the tumor necessitated hip disarticulation 3 years after the initial procedure. We then performed a histologic analysis of the transplant. The growth plate was still normal in structure but had richly vascularized hyperplastic layers. We observed bridging between the articular cartilage and the growth plate.
