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Identifying protein-protein interaction sites in transient complexes with temperature factor, sequence profile and

Rong Liu1, Wenchao Jiang, Yanhong Zhou

  • 1Hubei Bioinformatics and Molecular Imaging Key Laboratory, College of Life Science and Technology, Huazhong University of Science and Technology, 430074, Wuhan, China. Liurong116@tom.com

Amino Acids
|February 14, 2009
PubMed
Summary

Researchers identified the temperature factor (B-factor) as a key feature for predicting transient protein-protein interactions. Incorporating B-factor alongside sequence profile and accessible surface area significantly improves prediction accuracy for these vital biological interactions.

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