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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
Physiological predictors of maximum treadmill walking performance in patients with intermittent claudication
G A Tew1, S Nawaz, M Blagojevic
1Centre for Sport and Exercise Science, Sheffield Hallam University, United Kingdom.
International Journal of Sports Medicine
|February 14, 2009
Summary
Cardiopulmonary fitness and calf muscle oxygenation predict maximum walking distance in patients with intermittent claudication. Near-infrared spectroscopy (NIRS) measures can help assess treatment effectiveness.
Area of Science:
- Vascular Medicine
- Exercise Physiology
- Biomedical Engineering
Background:
- Intermittent claudication (IC) significantly impairs walking ability.
- Identifying physiological predictors of walking performance in IC is crucial for effective treatment.
Purpose of the Study:
- To identify physiological predictors of maximum treadmill walking performance (MWD) in patients with IC.
- To explore the utility of near-infrared spectroscopy (NIRS) in assessing IC.
Main Methods:
- Forty-five IC patients underwent graded treadmill tests to assess MWD, peak oxygen uptake, and gas exchange threshold.
- Calf muscle oxygenation (StO2) using NIRS, peak calf blood flow, ankle-brachial index, and pulmonary oxygen uptake kinetics were measured.
- Forward stepwise multiple regression analysis was used to determine MWD predictors.
Main Results:
- A regression model including time to minimum StO2, peak oxygen uptake, and StO2 at 1 min explained 64% of the variation in MWD.
- Cardiopulmonary fitness and oxygen delivery/utilization balance are key determinants of walking performance in IC.
Conclusions:
- Peak oxygen uptake and NIRS-derived calf muscle oxygenation parameters are significant predictors of MWD in IC patients.
- NIRS variables may be valuable for evaluating treatment efficacy and understanding mechanisms of improvement in IC.
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Introduction
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Definition
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Purposes
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes