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Comparative Strategies for Ubiquitination Detection in Mammalian Cell Lysates Using SMAD2/SMURF2 as a Model
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Small ubiquitin-like modifiers in cellular malignancy and metastasis.

Keun Il Kim1, Sung Hee Baek

  • 1Department of Biological Sciences, Research Center for Women's Disease, Sookmyung Women's University, Seoul, Korea.

International Review of Cell and Molecular Biology
|February 14, 2009
PubMed
Summary

The Small Ubiquitin-like Modifier (SUMO) system regulates cellular functions and homeostasis. Dysregulation of SUMOylation contributes to cancer development, progression, and metastasis, highlighting its critical role in oncology.

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