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Published on: April 7, 2023
Spontaneous remission of diabetes insipidus due to CNS sarcoidosis
Hidefumi Inaba1, Satoru Suzuki, Satoshi Shigematsu
1Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School of Medicine, Matsumoto. dinaba@hsp.md.shinshu-u.ac.jp
Abstract:
Central nervous system (CNS) sarcoidosis is a crucial disease and has a poor prognosis. A 58-year-old woman had acute development of polydipsia and polyuria. Her pituitary MRI demonstrated a swelling of pituitary gland and hypophyseal stalk. She was diagnosed as central diabetes insipidus (CDI) due to CNS sarcoidosis based on the examinations and pituitary MRI findings as well as a result of cutaneous biopsy. Uveitis and bilateral hilar lymphadenopathy were observed mildly throughout. However, CDI and pituitary MRI findings were getting recovered spontaneously without steroid treatment in a couple of months, suggesting an atypical clinical course of CNS sarcoidosis.
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