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Updated: Jun 25, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
[Treatment practice in primary hyperparathyroidism]
Haakon M Lindekleiv1, Jan Due, Johan Svartberg
1Avdeling for urologi og endokrin kirurgi, Universitetssykehuset Nord-Norge, 9038 Tromsø.
Norwegian surgeons and endocrinologists show varied approaches to primary hyperparathyroidism surgery. Despite good agreement on indications, unexplained regional differences in surgical frequency persist, not aligning with international guidelines.
Area of Science:
- Endocrinology
- Surgical Practice
- Healthcare Management
Context:
- Significant regional variations in primary hyperparathyroidism (PHP) treatment exist in Norway.
- Lack of consensus on surgical indications for PHP.
- Previous studies highlight disparities in PHP management.
Purpose:
- To survey Norwegian endocrine surgeons and endocrinologists regarding their opinions on surgical treatment indications for PHP.
- To investigate factors contributing to regional differences in PHP surgery rates.
- To assess adherence to international guidelines for PHP surgical treatment.
Summary:
- A questionnaire was distributed to 46 surgeons and endocrinologists across 17 Norwegian hospitals concerning PHP preoperative evaluation and surgical indications.
- While surgeons and endocrinologists showed agreement on indications, neither group strictly followed international guidelines.
- Differences in preoperative evaluations and indications did not correlate with regional surgery frequencies, and patients in high-frequency hospitals were often diagnosed in surgical departments.
Impact:
- Findings suggest that variations in clinical practice and adherence to guidelines do not fully explain regional disparities in PHP surgery rates.
- Highlights the need for further research into the drivers of regional variations in surgical treatment for PHP.
- Informs potential strategies for standardizing PHP care and improving patient outcomes across different regions.
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