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Updated: Jun 25, 2026

Alignment of Visible-Light Optical Coherence Tomography Fibergrams with Confocal Images of the Same Mouse Retina
Published on: June 30, 2023
In-fiber common-path optical coherence tomography using a conical-tip fiber.
1SUPA, School of Physics and Astronomy, University of St. Andrews, North Haugh, St. Andrews, Fife, KY16 9SS, UK. kmt10@st-andrews.ac.uk
This study introduces an in-fiber common-path optical coherence tomography (CPOCT) technique using a conical lens-tip fiber. This method eliminates the need for an extra cover glass, simplifying setup for endoscopic OCT imaging.
Area of Science:
- Biomedical Optics
- Optical Engineering
- Medical Imaging
Background:
- Common-path optical coherence tomography (CPOCT) minimizes dispersion and polarization mismatch by sharing optical paths.
- Conventional CPOCT requires an additional cover glass in the sample arm for a reference signal.
- This adds complexity and potential artifacts to the imaging system.
Purpose of the Study:
- To develop a simplified CPOCT technique by eliminating the need for an external reference cover glass.
- To utilize the back-reflected signal from a specialized fiber tip as the reference.
- To demonstrate the feasibility of this in-fiber CPOCT for biological tissue imaging.
Main Methods:
- A conical lens was fabricated directly onto an optical fiber tip using selective-chemical etching.
- This conical lens served dual roles: imaging lens and self-aligning reference plane.
- A Fourier-domain OCT system was employed to test the in-fiber CPOCT technique on biological samples.
Main Results:
- The conical lens-tip fiber successfully generated a reference signal without an additional cover glass.
- The technique demonstrated feasibility for imaging biological tissues.
- The in-fiber CPOCT system effectively reduced setup complexity.
Conclusions:
- The proposed in-fiber CPOCT technique offers a simplified approach to OCT imaging.
- This method holds significant potential for applications in endoscopic OCT.
- Further development could enhance its utility in minimally invasive medical procedures.
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