Related Experiment Video
Updated: Jun 25, 2026
Transvaginal Mesh Insertion in the Ovine Model
Published on: July 27, 2017
Experimental biomechanical evaluation of polypropylene prostheses used in pelvic organ prolapse surgery
Fabrice Sergent1, Nicolas Desilles, Yann Lacoume
1Clinique Gynécologique et Obstétricale, CHU-Hôpitaux de Rouen, 1 Rue de Germont, 76031 Rouen Cedex, France. Fabrice.Sergent@chu-rouen.fr
Introduction And Hypothesis:
Although polypropylene (PP) is the most common biomaterial used to repair genital prolapse via vaginal route, its mechanical properties however remain obscure.
Methods:
An abdominal hernia rabbit model was used to evaluate retraction, solidity, and elasticity of the principal types of PP prostheses currently available, i.e., three large pore size monofilament prostheses, one heavy weight (HWPP), a second low weight (LWPP), and a third coated with atelocollagen (CPP). A small pore size multifilament PP (MPP) implant was also tested.
Results:
In comparison with HWPP (12%), LWPP (15%), and MPP (30%), CPP had less retraction (8% of the original size). Unlike pore size, weight prosthesis is not an influencing factor for retraction. Atelocollagen coating reduced retraction. HWPP and MPP were the most solid prostheses. MPP supported the greatest elastic force.
Conclusions:
When the biomechanical parameters were comparatively assessed, HWPP was considered to have the most advantageous properties for prolapse surgery.
