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Published on: December 22, 2016
[Correlation factors of electrical status epilepticus during sleep in children]
Shuang Zhang1, Bao-Dong Pang, Li-Hua Cao
1Maternal and Child Health Care Hospital of Tangshan, Tangshan, Hebei 063000, China. zhangshuang2970@sina.com
Insights
Electrical status epilepticus during sleep (ESES) in children may be linked to a family history of epilepsy, specific epileptic syndromes, and developmental issues like language disorder and mental retardation.
Area of Science:
- Pediatric Neurology
- Epileptology
Context:
- The underlying causes of electrical status epilepticus during sleep (ESES) in children are not well understood.
- ESES is a specific EEG pattern observed during sleep in children with epilepsy.
Purpose:
- To investigate potential correlation factors associated with the occurrence of ESES in pediatric epilepsy patients.
- To compare clinical and historical data between children with ESES and a matched control group without ESES.
Summary:
- A retrospective study compared 30 epileptic children with ESES to 30 matched controls.
- Children with ESES showed a significantly higher prevalence of family history of epilepsy, language disorder, epileptic syndromes, and mental retardation compared to controls.
Impact:
- Findings suggest that family history, epileptic syndromes, mental retardation, and language disorder are potential contributing factors to ESES in children.
- This research may guide future diagnostic and therapeutic strategies for pediatric epilepsy management.
Objective:
The pathogenesis of electrical status epilepticus during sleep (ESES) in children remains unknown. We undertook a retrospective study of epileptic children who presented with ESES to investigate the correlation factors of ESES.
Methods:
Thirty epileptic children with ESES (ESES group) and 30 age-and sex-matched epileptic children without ESES (control group) admitted to Maternal and Child Health Care Hospital of Tangshan between January 2000 and July 2006 were enrolled. The results of questionnaire and laboratory examinations were compared between the two groups.
Results:
Nine patients had a family history of epilepsy in the ESES group, but only 2 patients in the control group (<0.05). Language disorder was found in 11 patients in the ESES group, but only 2 patients in the control group (<0.05). Thirteen patients were confirmed with epileptic syndrome in the ESES group, but only 5 patients in the control group (<0.05). Twenty five patients in the ESES group showed mental retardation, but only 5 patients from the control group (<0.01).
Conclusions:
ESES may be correlated with family history of epilepsy, epileptic syndrome, mental retardation and language disorder.
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