Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Reporter Genes

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A sensitive orange fluorescent calcium ion indicator for imaging neural activity.

Nature communications·2026

Same author

A Genetically Encoded Calcium Ion Biosensor with an Exceptionally Large Ratiometric Response.

ACS sensors·2026

Same author

PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities.

Nature methods·2026

Same author

Publisher Correction: A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics.

Nature communications·2025

Same author

A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular L-lactate dynamics.

Nature communications·2025

Same author

Bipartite Genetically Encoded Biosensors to Sense Calcium Ion Dynamics at Membrane-Membrane Contact Sites.

Analytical chemistry·2025

Search research articles

Related Experiment Video

Updated: Jun 25, 2026

FRET Microscopy for Real-time Monitoring of Signaling Events in Live Cells Using Unimolecular Biosensors

FRET Microscopy for Real-time Monitoring of Signaling Events in Live Cells Using Unimolecular Biosensors

Published on: August 20, 2012

Genetically encoded FRET-based biosensors for multiparameter fluorescence imaging.

Haley J Carlson¹, Robert E Campbell

¹University of Alberta, Department of Chemistry, Edmonton, Alberta, Canada.

Current Opinion in Biotechnology

|February 19, 2009

Summary

Förster (fluorescence) resonance energy transfer (FRET) biosensors enable live cell imaging of intracellular events. Combining FRET biosensors allows simultaneous multiparameter analysis, overcoming technological challenges for advanced cell biology research.

Failed At:

2026-06-19T13:42:37.874810+00:00

More Related Videos

Wide-Field, Real-Time Imaging of Local and Systemic Wound Signals in Arabidopsis

Wide-Field, Real-Time Imaging of Local and Systemic Wound Signals in Arabidopsis

Published on: June 4, 2021

Related Experiment Videos

Last Updated: Jun 25, 2026

FRET Microscopy for Real-time Monitoring of Signaling Events in Live Cells Using Unimolecular Biosensors

FRET Microscopy for Real-time Monitoring of Signaling Events in Live Cells Using Unimolecular Biosensors

Published on: August 20, 2012

Wide-Field, Real-Time Imaging of Local and Systemic Wound Signals in Arabidopsis

Wide-Field, Real-Time Imaging of Local and Systemic Wound Signals in Arabidopsis

Published on: June 4, 2021