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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Pulmonary hypertension and pregnancy
1Department of Cardiothoracic Medicine, St George's Hospital, London, UK. brendan.madden@stgeorges.nhs.uk
International Journal of Obstetric Anesthesia
|February 19, 2009
Summary
Pulmonary hypertension, a serious condition with poor prognosis, requires careful monitoring during pregnancy. Targeted therapies may be needed, but many drugs are contraindicated for pregnant women.
Area of Science:
- Cardiology
- Obstetrics
- Pathology
Background:
- Pulmonary hypertension (PH) is defined by elevated mean pulmonary artery pressure (>25 mmHg resting, >30 mmHg exercise).
- Plexogenic pulmonary arteriopathy underlies the most severe forms of PH.
- Delayed diagnosis of PH is common and associated with a poor prognosis.
Purpose of the Study:
- To review the risks and management of pulmonary hypertension in pregnancy.
- To highlight the importance of multidisciplinary care and specialized input.
Main Methods:
- Literature review focusing on the pathophysiology, diagnosis, and management of pulmonary hypertension in pregnant patients.
- Analysis of risks associated with specific therapies and delivery.
Main Results:
- Pulmonary hypertension poses significant risks to both mother and fetus.
- Many common PH treatments are contraindicated during pregnancy due to teratogenicity or excretion in breast milk.
- Optimal delivery mode remains unclear, necessitating early high-risk obstetric and anesthesia team involvement.
Conclusions:
- Pregnant women with pulmonary hypertension require vigilant monitoring by a multidisciplinary team.
- Careful consideration of therapeutic options is crucial, balancing maternal and fetal well-being.
- Early consultation with high-risk obstetric and anesthesia specialists is essential for optimal management and delivery planning.
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