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Insufficient control of blood pressure and incident diabetes

Raffaele Izzo1, Giovanni de Simone, Marcello Chinali

  • 1Department of Clinical Medicine, Cardiovascular, and Immunological Sciences, Federico II University-Naples, Naples, Italy.

Diabetes Care
|February 19, 2009
PubMed

Insights

Uncontrolled blood pressure in treated hypertensive patients significantly increases the risk of developing type 2 diabetes. Maintaining controlled blood pressure is crucial for preventing diabetes incidence.

Area of Science:

  • Cardiovascular Medicine
  • Endocrinology
  • Public Health

Background:

  • Hypertension is a known risk factor for type 2 diabetes.
  • The impact of blood pressure control on incident diabetes in treated hypertensive patients remains unclear.

Purpose of the Study:

  • To investigate the association between blood pressure control and the incidence of type 2 diabetes in patients with hypertension.

Main Methods:

  • A cohort of 1,754 non-diabetic hypertensive patients was followed for 3.4 years.
  • Blood pressure was classified as uncontrolled if systolic was ≥140 mmHg and/or diastolic was ≥90 mmHg.
  • Diabetes incidence was determined using American Diabetes Association criteria.

Main Results:

  • 41% of patients had uncontrolled blood pressure at baseline.
  • The incidence of diabetes was significantly higher in patients with uncontrolled blood pressure (8%) compared to those with controlled blood pressure (4%).
  • Uncontrolled blood pressure was independently associated with a twofold increased risk of incident type 2 diabetes (HR 2.10).

Conclusions:

  • In treated hypertensive individuals, uncontrolled blood pressure is a significant predictor of new-onset type 2 diabetes.
  • This association is independent of age, body mass index, baseline blood pressure, and fasting glucose levels.
Abstract

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