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Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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Liver growth factor antifibrotic activity in vivo is associated with a decrease in activation of hepatic stellate

Juan J Díaz-Gil1, Carmelo García-Monzón, Carmen Rúa

  • 1Department of Experimental Biochemistry, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain. jdiaz.hpth@salud.madrid.org

Histology and Histopathology
|February 19, 2009
PubMed
Summary

Liver Growth Factor (LGF) reduces liver fibrosis in bile duct-ligated rats by modulating fibrogenic liver cell activation. This antifibrotic effect was observed without impacting hepatic stellate cell proliferation.

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