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Updated: Jun 25, 2026
Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
Published on: February 17, 2013
Simultaneous vasomotor reactivity testing in the middle cerebral and basilar artery with suboccipital probe fixation
Ji Man Hong1, In Soo Joo, Kyoon Huh
1Department of Neurology, Ajou University School of Medicine, Suwon-sī, kyunggi-do, South Korea. dacda@hanmail.net
Background:
We assess the feasibility of using the newly designed suboccipital probe fixation device (SPFD) as a convenient and reliable tool for simultaneous measurement of vasomotor reactivity (VMR) in the middle cerebral artery (MCA) and basilar artery (BA).
Methods:
We analyzed 30 healthy volunteers' VMR values by using both SPFD and conventional handheld method. The VMR values were measured as percentage increase of the mean flow velocity on transcranial Doppler (TCD) in response to hypercapnia induced by the rebreathing method. The VMR tests were performed three times: (1) for both MCAs, (2) for the index MCA (the better signal window) and the BA by using the SPFD, and (3) for the index MCA and the BA by using the handheld technique.
Results:
The VMR values of the right and left MCAs were similar (P > .05). Although the VMR values of the index MCA and the BA obtained by SPFD application and the handheld technique were similar (P > .05), the correlation coefficient of VMR values obtained by using the SPFD was higher (r= .827, P < .001 vs. r= .568, P= .001).
Conclusion:
The SPFD is a convenient and reliable tool for the evaluation of relative VMR between the MCA and BA during TCD monitoring.
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