Related Experiment Video
Updated: Jun 25, 2026

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats
Published on: May 23, 2025
Iron Foreign Body in the Optic Nerve without Ocular Siderosis
Yih-Shiou Hwang1, Ken-Kuo Lin, Kuan-Jen Chen
1Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan, China. yihshiou.hwang@gmail.com
Background And Purpose:
An intraocular iron foreign body may cause many ocular complications, sometimes even blindness. Therefore, if possible, it should be removed to avoid ocular siderosis. We report a case in which a foreign body was trapped in the optic nerve and could not be removed. After a 2-year follow-up, no ocular siderosis or progressive deterioration in vision was found. This is the first case report of a foreign body in the optic nerve behind the eyeball in the PubMed literature.
Methods:
The authors describe the case of a 33-year-old man with an ocular trauma history at work. A metal iron foreign body was trapped in the optic nerve behind the eyeball, which was demonstrated by computed tomography.
Results:
There was no significant vision change and ocular siderosis by electroretinogram after 2 years of follow-up.
Conclusions:
Intra-optic-nerve foreign body may have a better ocular prognosis. Siderosis may not be seen in patients with optic nerve iron foreign body. Intraocular foreign body should be accurately studied before surgical procedures.
Related Concept Videos
Glaucoma: Overview
Anatomy of the Eyeball
Photoreceptors and Visual Pathways
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...

