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Published on: September 27, 2024
Fractional deep dermal ablation induces tissue tightening
Zakia Rahman1, Heather MacFalls, Kerrie Jiang
1Department of Dermatology, Stanford University, Stanford Medical School, Stanford, California 94305, USA.
Lasers in Surgery and Medicine
|February 20, 2009
Summary
Fractional deep dermal ablation (FDDA) offers a safer alternative to traditional skin resurfacing. This new laser treatment effectively improves photodamaged skin with minimal adverse events.
Area of Science:
- Dermatology
- Laser Technology
- Aesthetic Medicine
Background:
- Traditional ablative resurfacing carries significant risks.
- Fractional deep dermal ablation (FDDA) was developed as a safer, less invasive alternative.
- This study investigates FDDA for treating photodamaged skin.
Purpose of the Study:
- To evaluate the safety and efficacy of fractional deep dermal ablation (FDDA) for skin resurfacing.
- To assess clinical and histological outcomes of FDDA in treating photodamaged skin.
- To compare FDDA with traditional ablative resurfacing methods.
Main Methods:
- A prototype fractional CO(2) laser device was used for treatments.
- Initial treatments were performed on forearms, followed by a multi-center study on faces and necks.
- Subjects received 1-2 treatments with varying energy densities and densities.
- Clinical and histological assessments were conducted at multiple follow-up points.
- Improvement in rhytides, pigmentation, texture, laxity, and overall appearance was evaluated.
Main Results:
- FDDA demonstrated an improved safety profile compared to traditional ablative resurfacing.
- Both epidermal and dermal tissue resurfacing were effectively achieved.
- Treatments were well-tolerated, with no serious adverse events reported.
- Eighty-three percent of subjects showed moderate or better overall improvement.
Conclusions:
- Fractional deep dermal ablation (FDDA) is a safe and promising treatment for skin resurfacing.
- FDDA effectively targets both epidermal and deep dermal tissue.
- This modality represents a significant advancement in treating photodamaged skin.

