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Acute aggravation of subdural effusion associated with pachymeningitis carcinomatosa: case report
Neurosurgery
|September 1, 1991
Abstract:
The authors present a case of acute aggravation of subdural effusion associated with pachymeningitis carcinomatosa. Microscopic examination of a surgical specimen revealed diffuse involvement of the dura mater by a metastatic adenocarcinoma in which the tumor cells invaded venules located in the areolar layer in particular. The rapid increase in capillary transmural pressure resulted in extravasation of plasma components, causing an increase in subdural effusion.
Insights
This study details a rare case of subdural effusion worsening due to pachymeningitis carcinomatosa. Metastatic adenocarcinoma cells invading dural venules caused increased capillary pressure and plasma leakage, leading to effusion.
Area of Science:
- Neuropathology
- Oncology
- Neurosurgery
Background:
- Pachymeningitis carcinomatosa is a rare condition involving cancer spread to the dura mater.
- Subdural effusion can be a complication of dural pathologies.