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Related Concept Videos

Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
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Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

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Related Experiment Video

Updated: Jun 25, 2026

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions
09:56

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

Published on: August 12, 2010

Toxoplasmosis in immunocompromized patients.

Benjamin Edvinsson1, Maija Lappalainen, Veli-Jukka Anttila

  • 1Centre for Microbiological Preparedness, Swedish Institute for Infectious Disease Control, Solna, Sweden.

Scandinavian Journal of Infectious Diseases
|February 21, 2009
PubMed
Summary

Toxoplasma gondii infections pose severe risks to immunocompromised individuals, complicating diagnosis due to vague symptoms. Early monitoring of at-risk patients is crucial for timely intervention and improved outcomes.

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3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
06:33

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

Published on: December 9, 2014

Related Experiment Videos

Last Updated: Jun 25, 2026

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions
09:56

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

Published on: August 12, 2010

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
06:33

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

Published on: December 9, 2014

Area of Science:

  • Infectious Diseases
  • Parasitology
  • Immunology

Background:

  • Toxoplasma gondii is a widespread parasite with serious implications for immunocompromised patients.
  • Diagnosis of toxoplasmosis is difficult due to non-specific clinical presentations.

Observation:

  • This study details 8 cases of toxoplasmosis in immunocompromised individuals.
  • The non-specific nature of symptoms presented diagnostic challenges.

Findings:

  • The presented cases highlight the critical need for vigilant monitoring in immunocompromised populations.
  • Effective preventive monitoring strategies are essential for early detection and management.

Implications:

  • Implementing targeted monitoring protocols can improve the prognosis for immunocompromised patients at risk of toxoplasmosis.
  • This research underscores the importance of proactive surveillance in managing opportunistic infections.