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[Graze with unusual progress].
Teresa Løvold Berents1, Karianne Nodenes
1Hudavdelingen, Rikshospitalet, 0027 Oslo. tberents@rikshospitalet.no
Summary
Dibrompropamidine, an antiseptic in Brulidine cream, can cause allergic contact dermatitis. This article details two cases and diagnostic methods for this underreported adverse reaction to over-the-counter wound treatments.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Traumatic wounds are common and prone to infection, delaying healing.
- Antiseptic treatments, like Brulidine cream containing dibrompropamidine, are frequently sought at pharmacies.
- Dibrompropamidine is an over-the-counter (OTC) active ingredient used for local skin infections.
Observation:
- Contact allergy to dibrompropamidine has been reported.
- The OTC availability of dibrompropamidine may lead to underreporting of allergic reactions.
- Two cases of patient contact allergy to dibrompropamidine are presented.
Findings:
- The presented cases highlight the potential for allergic contact dermatitis from dibrompropamidine.
- Diagnostic procedures, including User tests and patch testing, are crucial for identifying contact dermatitis.
- Accurate diagnosis is essential for managing adverse reactions to topical antiseptics.
Implications:
- Healthcare providers should be aware of potential dibrompropamidine allergies.
- Patch testing is a valuable tool for diagnosing contact dermatitis to OTC medications.
- Improved reporting and awareness are needed for OTC drug-induced allergies.
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