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Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
Published on: April 4, 2019
Impact of RSV: implications for managed care
Doris Makari1, J Michael Hoopes, Norman White
1Medical and Scientific Affairs, Medlmmune, LLC.
Managed Care (Langhorne, Pa.)
|February 24, 2009
Summary
Infants born prematurely are at high risk for severe respiratory syncytial virus (RSV) disease, leading to significant healthcare costs. Proactive RSV management can improve infant health outcomes and reduce hospitalizations.
Area of Science:
- Pediatrics
- Public Health
- Infectious Diseases
Background:
- Severe respiratory syncytial virus (RSV) disease, including bronchiolitis and pneumonia, is a primary cause of infant hospitalizations in the U.S.
- Infants born at or before 35 weeks' gestational age (GA) face elevated risks for severe RSV illness.
Purpose of the Study:
- To highlight the significant healthcare costs associated with RSV hospitalizations in preterm infants.
- To inform managed care payers about the economic impact of severe RSV disease in infants.
Main Methods:
- The study analyzed healthcare utilization and costs related to RSV hospitalizations in infants.
- Cost comparison between infants with and without a history of RSV hospitalization was performed.
Main Results:
- Infants born between 33 to 36 weeks GA with prior RSV hospitalization incurred costs nearly five times higher than those without.
- Preterm infants are vulnerable to severe RSV, leading to potential NICU admissions and prolonged hospital stays.
Conclusions:
- Managed care payers must recognize the substantial financial and health implications of severe RSV in infants.
- Implementing proactive RSV management strategies is crucial for enhancing infant health and optimizing hospital resource allocation.
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