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Updated: Jun 25, 2026

Levator Auris Longus Preparation for Examination of Mammalian Neuromuscular Transmission Under Voltage Clamp Conditions
Published on: May 5, 2018
[Energetic applications: Na+/K+-ATPase and neuromuscular transmission]
P Rigoard1, M Chaillou, M Fares
1Service de neurochirurgie, CHU La Milétrie, 2, rue de La Milétrie, BP 577, 86021 Poitiers cedex, France. p.rigoard@chu-poitiers.fr
Abstract:
Na/K-ATPase electrogenic activity and its indispensable role in maintaining gradients suggest that the modifications in isoform distribution and the functioning of the sodium pump have a major influence on both the neuronal functions, including excitability, and motor efficiency. This article proposes to clarify the involvement of Na/K-ATPase in the transmission of nerve influx within the peripheral nerve and then in the genesis, the maintenance, and the physiology of muscle contraction by comparing the data found in the literature with our work on neuron and muscle characterization of Na/K-ATPase activity and isoforms.
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