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Does tumor type affect local control by radiofrequency ablation in the lungs?
Takao Hiraki1, Hideo Gobara, Hidefumi Mimura
1Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan. takaoh@tc4.so-net.ne.jp
European Journal of Radiology
|February 24, 2009
Summary
Radiofrequency ablation (RFA) is effective for lung tumors. While colorectal cancer metastases showed higher initial local control, tumor type did not ultimately impact long-term outcomes after RFA.
Area of Science:
- Interventional Radiology
- Oncology
- Pulmonary Medicine
Background:
- Radiofrequency ablation (RFA) is a minimally invasive treatment for lung tumors.
- Evaluating factors influencing local control after RFA is crucial for treatment optimization.
Purpose of the Study:
- To retrospectively assess the impact of different tumor types on local control following lung radiofrequency ablation.
Main Methods:
- Retrospective analysis of 252 lung tumors in 105 patients treated with RFA.
- Tumor types included primary lung cancer and metastases from colorectal, lung, renal cell, and hepatocellular cancers.
- Local control assessed via CT, analyzed using Kaplan-Meier and multivariate analysis.
Main Results:
- Overall local control rates were 97% at 6 months, decreasing to 76% at 24 months.
- Metastatic colorectal cancer demonstrated significantly higher local control rates initially (P=.023).
- Multivariate analysis revealed no significant difference in local progression risk among tumor types.
Conclusions:
- Tumor type alone does not significantly influence the long-term local control achieved with radiofrequency ablation in lung tumors.
