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Updated: Jun 25, 2026
Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
Published on: December 28, 2014
Crossed cerebellar hyperperfusion on ictal FDG PET in astrocytoma
Michael Lin1, Tracy Smith, Roy G Beran
1Department of PET and Nuclear Medicine, Liverpool Hospital, University of New South Wales, 1 Elizabeth Drive, Liverpool, New South Wales 2170, Australia. michael.lin@swsahs.nsw.gov.au
Abstract:
Crossed cerebellar hyperperfusion (CCH) is a rare phenomenon and reflects the close anatomical and functional relationship between the frontal brain region and its mediated remote effect on the contralateral cerebellum via the corticopontocerebellar pathway. Although it is well documented on cerebral single photon emission tomography (SPECT) in patients with epilepsy, it is rarely observed in seizures originating from brain tumours. We report a 41-y-old man who whilst undergoing (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) for investigation of suspected glioma, developed a generalized seizure. The scan performed shortly after seizure onset demonstrated intense metabolic activity in the right superior frontal lobe and in the contralateral cerebellar hemisphere consistent with CCH.
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