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Updated: Jun 25, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Transapical transcatheter mitral valve-in-valve implantation in a human
Anson Cheung1, John G Webb, Daniel R Wong
1Division of Cardiac Surgery, St Paul's Hospital, University of British Columbia, Vancouver, Canada. acheung@providencehealth.bc.ca
Abstract:
We describe a human transcatheter transapical mitral valve implant within a mitral bioprosthesis (valve-in-valve). A high-risk, 80-year-old man with symptomatic bioprosthetic mitral stenosis was positioned for anterior minithoracotomy. Left ventricular apical access was obtained. After balloon valvuloplasty, a cuffed, 26-mm Cribier-Edwards transcatheter valve (Edwards Lifesciences LLC, Irvine, CA) was deployed within the mitral xenograft, using rapid ventricular pacing. The transcatheter valve functioned properly postoperatively; however, the patient died of multiple organ dysfunction.
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