Related Experiment Video
Updated: Jun 25, 2026
Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
Published on: September 17, 2017
General chromatographic NMR method in liquid state for synthetic chemistry: polyvinylpyrrolidone assisted DOSY
Jari S Kavakka1, Ilkka Kilpeläinen, Sami Heikkinen
1Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, P.O. Box 55, FIN-00014, University of Helsinki, Finland.
Abstract:
A polymer assisted liquid state DOSY NMR technique, to extract the spectra of the individual components from mixtures in CDCl(3), is demonstrated. The enhancement of diffusion coefficient differences is achieved using a soluble polymer, polyvinylpyrrolidone, as the "stationary phase". The "separation" of analytes resembles normal-phase chromatography, for example, TLC. This method provides a fast, cheap, and simple technique to resolve the NMR spectra of complex mixtures.
More Related Videos
14:11Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
05:05Quantification of Polybutylene Adipate Terephthalate-based Micro- and Nano-plastics from Soil Using Proton Nuclear Magnetic Resonance Spectroscopy
Published on: June 6, 2025
