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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Related Experiment Video

Updated: Jun 25, 2026

Humanized Mediator Release Assay as a Read-Out for Allergen Potency
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Published on: June 29, 2021

Food hypersensitivity by inhalation.

Daniel A Ramirez1, Sami L Bahna1

  • 1Allergy & Immunology Section, Louisiana State University Health Science Center in Shreveport, 1501 Kings Highway, Shreveport, LA, USA.

Clinical and Molecular Allergy : CMA
|February 24, 2009
PubMed
Summary
This summary is machine-generated.

Food hypersensitivity through inhalation, even from mere smells, causes significant illness. Strict avoidance, epinephrine, and asthma control are crucial for managing this serious condition.

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Area of Science:

  • Allergy and Immunology
  • Respiratory Medicine
  • Environmental Health

Background:

  • Food hypersensitivity via inhalation is often underestimated.
  • Exposure occurs in diverse settings, including occupational and non-occupational environments.
  • Reactions range from mild to life-threatening.

Purpose of the Study:

  • To highlight the significance of food hypersensitivity by inhalation.
  • To discuss clinical manifestations and management strategies.
  • To emphasize the potential for de novo sensitization.

Main Methods:

  • Review of clinical observations and existing literature.
  • Analysis of exposure scenarios in various environments.
  • Correlation of predisposing factors with clinical outcomes.

Main Results:

  • Inhalation exposure to food allergens can trigger diverse symptoms.
  • Even minimal exposure, like smelling food, can cause reactions.
  • Asthma is a significant predisposing factor for severe reactions.
  • De novo sensitization through inhalation is a critical concern.

Conclusions:

  • Food inhalation hypersensitivity requires greater recognition and awareness.
  • Comprehensive management includes allergen avoidance and emergency preparedness.
  • Controlling asthma is vital for individuals with this condition.