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Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management
Michael R Hernandez1, Robert C Shamberger, Christian Seefelder
1Department of Anesthesiology, Perioperative, and Pain Medicine, Children's Hospital Boston, Boston, MA 02115, USA. mhernandez@dacc.uchicago.edu
Abstract:
Preoperative alpha- and beta-adrenergic receptor block with phenoxybenzamine and labetalol, the intraoperative course of a 4-month-old infant with neuroblastoma and elevated catecholamines causing sweating, hypertension, and tachycardia, are presented. We recommend determination of catecholamine levels and pretreatment with alpha-adrenergic and--if needed--beta-adrenergic receptor antagonists in infants with neuroblastoma and hypertension, tachycardia, or sweating.
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