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Increasing prevalence and associated risk factors for methicillin resistant Staphylococcus aureus bacteriuria
Jonathan C Routh1, Angela L Alt, Richard A Ashley
1Department of Urology, Mayo Clinic, Rochester, Minnesota, USA.
The Journal of Urology
|February 24, 2009
Summary
Methicillin-resistant Staphylococcus aureus (MRSA) bacteriuria remains rare but increased from 2007 to 2017. Older age, catheter use, hospital exposure, and comorbidities are key risk factors for MRSA urinary tract infections.
Area of Science:
- Infectious Diseases
- Urology
- Clinical Microbiology
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) is a growing public health concern in both hospital and community settings.
- Urinary tract infections (UTIs) are common, and understanding the causative agents is crucial for effective treatment.
Purpose of the Study:
- To investigate the changing incidence of MRSA as a cause of bacteriuria.
- To identify specific risk factors associated with the development of MRSA bacteriuria.
Main Methods:
- A retrospective review of urine cultures from 1997 and 2007 was conducted.
- Patients with MRSA bacteriuria were compared to those with methicillin-sensitive S. aureus (MSSA) and Escherichia coli (E. coli) bacteriuria.
- Multivariate analysis was used to identify associated risk factors.
Main Results:
- The incidence of MRSA bacteriuria increased significantly from 0.3% in 1997 to 0.8% in 2007.
- Escherichia coli remained the most common cause of bacteriuria.
- Older age, catheter use, hospital exposure, and patient comorbidity were significantly associated with MRSA bacteriuria compared to E. coli.
Conclusions:
- While MRSA bacteriuria is still uncommon, its incidence has risen over the past decade.
- Key risk factors for MRSA bacteriuria include advanced age, comorbidities, hospital exposure, and catheter use.
- Clinicians should consider MRSA in patients with these risk factors presenting with new urinary symptoms.
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