Related Experiment Video
Updated: Jun 25, 2026

Method of Isolated Ex Vivo Lung Perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program
Published on: February 25, 2015
Escape rhythm from a partially disconnected pulmonary vein
Yoav Michowitz1, Aharon Glick, Bernard Belhassen
1The Department of Cardiology, Tel Aviv Sourasky Medical Center and The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. ymichowitz@gmail.com
A rare case of pulmonary vein (PV) escape rhythm occurred during atrial fibrillation treatment. This finding suggests that a dissociated PV rhythm does not always indicate complete PV isolation after ablation.
Area of Science:
- Electrophysiology
- Cardiac Arrhythmias
- Interventional Cardiology
Background:
- Drug-refractory paroxysmal atrial fibrillation necessitates pulmonary vein (PV) isolation.
- Pulmonary vein isolation is a standard treatment for atrial fibrillation.
- Recurrent atrial fibrillation poses a significant clinical challenge.
Observation:
- During a pulmonary vein isolation procedure, a dissociated escape rhythm was noted in a portion of the right superior PV.
- This rhythm originated from a section of the PV that was only partially disconnected.
- Conduction from the left atrium to the PV was still present in other parts of the same PV.
Findings:
- Demonstrates a rare instance of an escape rhythm originating from a partially disconnected pulmonary vein.
- Highlights that dissociated pulmonary vein rhythm can occur even without complete electrical isolation.
- Challenges the assumption that any observed dissociated rhythm signifies successful pulmonary vein isolation.
Implications:
- Suggests a need for careful electrophysiological assessment during and after pulmonary vein isolation procedures.
- May necessitate modifications in ablation strategies to ensure complete pulmonary vein disconnection.
- Underscores the complexity of pulmonary vein electrical activity and ablation outcomes.
More Related Videos
10:02Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow
Published on: April 29, 2011
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Related Concept Videos
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Overview of Systemic and Pulmonary Circulation
The oxygenated blood is sent...
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Dysrhythmias IV: Characteristics of Bradyarrhythmias
Overview of Pulmonary Circulation
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
The Cardiac Cycle
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and empty blood into the...