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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...

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Related Experiment Video

Updated: Jul 3, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
16:40

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

Published on: February 28, 2012

Leadless Pacemaker Implantation in High-Risk Patients: Real-World Outcomes From a Multicenter Israeli Registry.

Moshe Katz1,2, Marianna Vander3,4, David Luria3,4

  • 1Gray School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Pacing and Clinical Electrophysiology : PACE
|July 2, 2026
PubMed
Summary

Leadless pacemakers offer a safe and effective alternative for high-risk patients unsuitable for traditional pacing. This study shows high success and low complication rates in a challenging cohort.

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Related Experiment Videos

Last Updated: Jul 3, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
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Translational Rabbit Model of Chronic Cardiac Pacing
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Published on: January 6, 2023

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Published on: October 16, 2021

Area of Science:

  • Cardiology
  • Medical Devices
  • Electrophysiology

Background:

  • Transvenous pacemakers have limitations and complications.
  • Leadless pacemakers aim to reduce these issues.
  • Data on leadless pacemakers in high-risk patients are limited.

Purpose of the Study:

  • To assess real-world outcomes of leadless pacemakers.
  • Focus on high-risk bradyarrhythmia patients ineligible for transvenous pacing.

Main Methods:

  • Retrospective, observational, multi-center registry (MLPI) in Israel.
  • Included 138 patients from July 2021-December 2022.
  • Assessed procedural success, complications, electrical performance, and mortality at 48h, 30 days, and 12 months.

Main Results:

  • High comorbidity burden (hypertension, heart failure, CKD).
  • Successful implantation in 98% of patients; 4.7% cumulative complication rate at 1 year.
  • Stable electrical performance with low pacing thresholds and low mortality (12.3% all-cause at 1 year).

Conclusions:

  • Leadless pacemaker implantation is safe and effective in high-risk patients.
  • Achieved high procedural success and stable performance.
  • Supports leadless pacemakers as an alternative to conventional systems.