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Novel Approach to Lead Extraction, Utilizing Vibration Energy: From Bench Experiments to a First-in-Human Study.

Orr Tomer¹, Yair Elitzur¹, Andrzej Przybylski²

¹Department of Cardiology, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

JACC. Clinical Electrophysiology

|April 9, 2026

Summary

This summary is machine-generated.

A new vibration-based lead extraction technique shows high safety and success rates. This method avoids cutting tools, reducing risks associated with conventional lead extraction procedures.

Keywords:

novel extraction method transvenous lead extraction vibration energy

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Area of Science:

Cardiovascular medicine
Medical device technology
Surgical innovation

Background:

Conventional lead extraction methods use cutting tools, increasing risks of collateral damage and bleeding.
Existing techniques pose significant complications during lead removal.

Purpose of the Study:

To evaluate a novel vibration-based lead extraction technique.
Assess the safety and efficacy of this tool-less method.
Include preclinical and initial human data.

Main Methods:

Developed and tested vibration parameters in bench experiments.
Conducted animal studies (N=13) with long-term lead implants.
Performed a first-in-human study of 10 patients (18 leads).

Main Results:

Bench experiments optimized vibration parameters.
Animal studies confirmed safety and successful extraction of leads up to 5 years post-implantation.
Human study achieved 100% procedural success with no complications at 1-month follow-up.

Conclusions:

The vibration-based technique is safe and effective.
Offers a potentially simpler, faster, and safer alternative to traditional methods.
Demonstrates promise for improved lead extraction outcomes.