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Testosterone gel for the treatment of male hypogonadism
1VU University Medical Center, Department of Endocrinology, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands. p.deronde@vumc.nl
Background:
Testosterone supplementation is a standard treatment for young men with hypogonadism and has also been advocated as a treatment for symptomatic older men with low testosterone levels. Several modes of testosterone replacement are available including capsules, patches, injections, buccal tablets and gels.
Objective:
To review the literature concerning therapeutic efficacy and potential limitations of testosterone gels.
Methods:
The FDA medical reviews and the computerised database PubMed were searched for clinical trials studying currently approved testosterone gels.
Results/Conclusions:
Testosterone gel has proved to be a valuable contribution to the existing modes of testosterone treatment, combining therapeutic efficacy, convenience and safety.
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