Related Experiment Video

Updated: Jun 25, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

[Pediatric dermatology. New aspects of bacterial skin infections in children]

H Hofmann1, C Schnopp

  • 1Klinik und Poliklinik für Dermatologie am Biederstein, TU München, München. Heidelore.Hofmann@lrz.tu-muenchen.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|February 25, 2009
PubMed

Insights

This review covers common pediatric bacterial skin infections like impetigo and Lyme disease. Early diagnosis and understanding pathogen resistance are key for effective treatment in children.

Area of Science:

  • Pediatric Dermatology
  • Infectious Diseases
  • Bacteriology

Context:

  • Bacterial skin infections are prevalent in children.
  • Common pathogens include Staphylococcus aureus, Streptococcus pyogenes, and Borrelia burgdorferi.
  • Accurate diagnosis and treatment are crucial for pediatric patients.

Purpose:

  • To review key aspects of bacterial skin diseases in children.
  • To highlight diagnostic challenges and treatment considerations for common pediatric skin infections.
  • To emphasize the importance of pathogen identification and local resistance patterns.

Summary:

  • Focuses on Staphylococcus aureus, Streptococcus pyogenes, and Borrelia burgdorferi as common causes of pediatric skin infections.
  • Discusses the variable presentation of erythema migrans in early Lyme borreliosis and its hematogenic spread.
  • Addresses impetigo treatment, considering comorbidities, pathogens, and resistance, noting the new topical antibiotic retapamulin.
  • Highlights underdiagnosed perianal streptococcal disease, emphasizing diagnosis via culture and penicillin treatment.

Impact:

  • Aids clinicians in the early and accurate diagnosis of pediatric bacterial skin diseases.
  • Informs treatment strategies by considering specific pathogens and local antibiotic resistance.
  • Improves management of impetigo and perianal streptococcal disease in children.
  • Enhances understanding of Lyme borreliosis presentation in pediatric populations.

More Related Videos

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...