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Updated: Jun 25, 2026

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum
Published on: April 10, 2018
Evaluation of commercially available anti-dengue virus immunoglobulin M tests
Elizabeth A Hunsperger1, Sutee Yoksan, Philippe Buchy
1Serology Diagnostics and Viral Pathogenesis Research Section, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Abstract:
Anti-dengue virus immunoglobulin M kits were evaluated. Test sensitivities were 21%-99% and specificities were 77%-98% compared with reference ELISAs. False-positive results were found for patients with malaria or past dengue infections. Three ELISAs showing strong agreement with reference ELISAs will be included in the World Health Organization Bulk Procurement Scheme.

