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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: Jun 25, 2026

Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function
07:31

Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function

Published on: March 10, 2026

Relationships between brain activation and brain structure in normally developing children.

Lisa H Lu1, Mirella Dapretto, Elizabeth D O'Hare

  • 1UCLA Laboratory of Neuro Imaging, Department of Neurology, Los Angeles, CA 90095, USA.

Cerebral Cortex (New York, N.Y. : 1991)
|February 26, 2009
PubMed
Summary
This summary is machine-generated.

Brain structure and activity mature together during development. This study found that mature brain morphology in children correlated with specific brain activation patterns during reading tasks, suggesting experience shapes these connections.

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Related Experiment Videos

Last Updated: Jun 25, 2026

Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function
07:31

Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function

Published on: March 10, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
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Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Cortical Source Analysis of High-Density EEG Recordings in Children
09:32

Cortical Source Analysis of High-Density EEG Recordings in Children

Published on: June 30, 2014

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Cognitive Science

Background:

  • Development involves dynamic changes in brain structure, activation, and cognitive abilities.
  • The relationship between structural brain changes, cognitive function, and brain activity during development is not well understood.

Purpose of the Study:

  • To integrate structural and functional magnetic resonance imaging (MRI) data with cognitive test scores in children.
  • To identify correlates of mature performance in orthographic processing by linking brain structure and function.

Main Methods:

  • Used cortical pattern matching to correlate cortical gray matter thickness with functional brain activity across the entire brain surface.
  • Analyzed data from 24 typically developing children, integrating MRI data with cognitive test scores.

Main Results:

  • Children who named novel fonts faster showed greater activation in the right fronto-parietal attention network.
  • Increased activation in this network correlated with more mature brain morphology in the same region, independent of age or general cognitive ability.

Conclusions:

  • Identified specific cortical regions where mature brain morphology corresponds to mature activation patterns.
  • Results suggest a potential role for experience in mediating the relationship between brain structure and activity during development.