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Cerebral neoplastic angioendotheleosis complicated by hypercalcaemia
A S Wierzbicki1, J M Gibbs, H G Lidov
1Department of Chemical Pathology, National Hospitals for Nervous Diseases, Queen Square, London, UK.
Postgraduate Medical Journal
|June 1, 1991
Summary
This case report details a 67-year-old man with altered consciousness and myoclonic jerks due to hypercalcemia. Neoplastic angioendotheliosis was diagnosed via brain biopsy, marking the first association with hypercalcemia.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Hypercalcemia can manifest with diverse neurological symptoms.
- Neoplastic angioendotheliosis is a rare vascular tumor affecting the brain.
Observation:
- A 67-year-old male presented with fluctuating consciousness and myoclonic jerks.
- Initial symptoms were attributed, in part, to severe hypercalcemia.
Findings:
- Cerebral neoplastic angioendotheliosis was diagnosed definitively through brain biopsy.
- This case represents the first documented instance of hypercalcemia associated with neoplastic angioendotheliosis.
Implications:
- Highlights the importance of considering metabolic disturbances like hypercalcemia in neurological presentations.
- Adds to the understanding of rare neoplastic angioendotheliosis and its potential systemic effects.
- Suggests further investigation into the mechanisms linking neoplastic angioendotheliosis and hypercalcemia.