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Updated: Jun 25, 2026

Imaging Metals in Brain Tissue by Laser Ablation - Inductively Coupled Plasma - Mass Spectrometry (LA-ICP-MS)
Published on: January 22, 2017
Laser ablation-inductively coupled plasma mass spectrometry in archaeometric research
Martín Resano1, Esperanza García-Ruiz, Frank Vanhaecke
1Department of Analytical Chemistry, University of Zaragoza, Pedro Cerbuna 12, E-50009 Zaragoza, Spain. mresano@unizar.es
Abstract:
Laser ablation-inductively coupled plasma mass spectrometry (LA-ICPMS) is a solid sampling technique in continuous expansion in all types of research fields in which direct multi-elemental or isotopic analysis is required. In particular, this technique shows unique characteristics that made its use recommended in many archaeometric applications, where valuable solid artifacts are often the target samples, because it offers flexibility to achieve spatially resolved information with high detection power and a wide linear range, in a fast and straightforward way, and with minimal sample damage. The current review provides a systematic survey of publications that reported the use of LA-ICPMS in an archaeological context, highlights its main capabilities and limitations and discusses the most relevant parameters that influence the performance of this technique for this type of application.
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