Related Experiment Video
Updated: Jun 25, 2026

Micro-CT Imaging and Morphometric Analysis of Mouse Neonatal Brains
Published on: May 19, 2023
[Brain morphometric characteristics of one-year-old infants (according to magnetic resonance tomography data)]
Insights
This study analyzed one-year-old infant brain development using MRI, revealing sex-based differences in brain structure size and right hemisphere dominance. These findings highlight early brain development variations in infants.
Area of Science:
- Neuroscience
- Developmental Biology
- Medical Imaging
Context:
- Understanding early brain development is crucial for identifying potential developmental abnormalities.
- Individual variations in brain structure can influence cognitive and motor functions.
- Magnetic Resonance Tomography (MRT) offers non-invasive in vivo insights into brain morphology.
Purpose:
- To provide an integrated intravital morphometric analysis of infant brains.
- To characterize sex-related and interhemispheric variations in brain dimensions.
- To establish a baseline for normal brain development in one-year-olds.
Summary:
- Magnetic Resonance Tomography (MRT) revealed significant sexual dimorphism in one-year-old infant brains.
- Boys exhibited larger telencephalic dimensions, while girls showed larger brainstem structures.
- Interhemispheric asymmetry was common, with a tendency for right hemisphere lobe prevalence.
Impact:
- Establishes normative data for infant brain morphometry, aiding in the early detection of developmental deviations.
- Provides insights into the neurodevelopmental trajectories influenced by sex and hemispheric asymmetry.
- Enhances understanding of individual variability in early brain growth and its potential implications.
Abstract:
The present study was designed to give the integrated intravital morphometric characteristic of the brain of one-year-old infants taking into account their individual variation (sex-related, interhemispheric) using magnetic resonance tomography. The research has revealed a sexual dimorphism of the brain dimensions: telencephalic dimensions were found to prevail in boys, while the dimensions of the brainstem structures were prevalent in girls. The interhemispheric asymmetry was detected in the brain of one-year-old infants; in most cases there was a prevalence of the dimensions of the right hemisphere lobes over those ones of the left hemisphere.
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Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...