Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physiological stress improves stem cell modeling of dystrophic cardiomyopathy.

Disease models & mechanisms·2023
Same author

Cardiomyocyte external mechanical unloading activates modifications of α-actinin differently from sarcomere-originated unloading.

The FEBS journal·2023
Same author

Transthyretin deposition alters cardiomyocyte sarcomeric architecture, calcium transients, and contractile force.

Physiological reports·2022
Same author

Striated muscle proteins are regulated both by mechanical deformation and by chemical post-translational modification.

Biophysical reviews·2021
Same author

Police Officers' addiction frameworks and policy attitudes.

Addictive behaviors·2021
Same author

Transthyretin amyloid fibrils alter primary fibroblast structure, function, and inflammatory gene expression.

American journal of physiology. Heart and circulatory physiology·2021
Same journal

Association of a Diet Index for the Gut Microbiome With Hypertension and Obesity-Related Hypertension: A Cross-Sectional Analysis of NHANES 2007-2020.

The Journal of cardiovascular nursing·2026
Same journal

Device-Assessed Physical Activity and Cardiometabolic Health in Chinese American Women With a History of Gestational Diabetes Mellitus.

The Journal of cardiovascular nursing·2026
Same journal

Physical Frailty, Self-Care Behaviors, and 6-Month Clinical Outcomes Among Adults With Heart Failure.

The Journal of cardiovascular nursing·2026
Same journal

Challenges Experienced by Patients With Chronic Venous Disease in Unresolved Postoperative Recovery After Iliac Vein Stenting: A Phenomenological Study.

The Journal of cardiovascular nursing·2026
Same journal

The Impact of Massage on Pain and Vital Signs Following Cardiovascular Surgery in Pediatric Patients.

The Journal of cardiovascular nursing·2026
Same journal

Prioritizing Cultural Relevance and Co-Production in Cardiovascular Technologies: A Call for Action.

The Journal of cardiovascular nursing·2026
See all related articles

Related Experiment Video

Updated: Jun 25, 2026

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
09:31

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Published on: March 30, 2018

Introduction to stem cell therapy.

Jesse K Biehl1, Brenda Russell

  • 1Department of Bioengineering, University of Illinois at Chicago, USA.

The Journal of Cardiovascular Nursing
|February 27, 2009
PubMed
Summary
This summary is machine-generated.

Stem cells possess self-renewal and differentiation abilities, crucial for tissue repair. Further research is needed to fully harness their therapeutic potential in regenerative medicine.

More Related Videos

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications
08:32

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications

Published on: August 9, 2022

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

Related Experiment Videos

Last Updated: Jun 25, 2026

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
09:31

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Published on: March 30, 2018

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications
08:32

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications

Published on: August 9, 2022

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

Area of Science:

  • * Stem cell biology and regenerative medicine.

Background:

  • * Stem cells are characterized by self-renewal and differentiation into specialized cell types.
  • * Two main classes exist: pluripotent (any cell type) and multipotent (limited cell types).

Purpose of the Study:

  • * To discuss stem cell sources, characteristics, differentiation, and therapeutic applications.
  • * To highlight the potential of stem cells in tissue regeneration and repair.

Main Methods:

  • * Review of stem cell properties, including self-renewal and differentiation capabilities.
  • * Examination of pluripotent and multipotent cell classifications.
  • * Discussion of current and potential therapeutic uses.

Main Results:

  • * Stem cells offer significant promise for tissue regeneration and repair applications.
  • * Understanding stem cell biology, manipulation, and safety is ongoing.

Conclusions:

  • * Stem cells hold great therapeutic potential, particularly in regenerative medicine.
  • * Continued research is essential to overcome challenges in stem cell manipulation and ensure safety for clinical application.