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Related Concept Videos

The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
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Spinal Nerves: Anatomy01:23

Spinal Nerves: Anatomy

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Sutures of the Skull01:22

Sutures of the Skull

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Published on: July 5, 2021

Chordomas involving multiple neuraxial bones.

Jae Joon Lim1, Sang Hyun Kim, Ki Hong Cho

  • 1Department of Neurosurgery, Ajou University School of Medicine, Suwon, Korea.

Journal of Korean Neurosurgical Society
|February 27, 2009
PubMed
Summary

This study details a rare case of multifocal osseous chordomas in a 62-year-old male affecting multiple bones. Treatment recommendations include radical resection or radiation therapy for these unusual bone tumors.

Keywords:
ChordomaJugular foramenMultipleParaclivalSacralThoracic

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Area of Science:

  • Oncology
  • Neurosurgery
  • Orthopedic Oncology

Background:

  • Chordomas are rare, slow-growing bone tumors arising from notochordal remnants.
  • Multifocal osseous chordomas are exceptionally rare, presenting diagnostic and therapeutic challenges.
  • Understanding the growth patterns and origins of multifocal chordomas is crucial for effective management.

Observation:

  • A 62-year-old male presented with multiple symptomatic osseous chordomas.
  • Lesions were identified in the sacral, thoracic, and paraclival jugular foramen regions.
  • No distant metastases were detected; all affected sites were osseous.

Findings:

  • The case represents an extremely rare instance of multicentric chordomas involving multiple neuraxial bones.
  • Unusual growth patterns were observed in the multifocal osseous lesions.
  • The findings suggest a potential for widespread osseous involvement without systemic metastasis.

Implications:

  • Radical resection of each lesion is recommended at initial diagnosis for multifocal chordomas.
  • Preoperative or postoperative radiation therapy should be considered when complete surgical resection is not feasible.
  • This case highlights the importance of considering multicentricity in the diagnosis and treatment planning for chordoma patients.