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Increased arterial oxygen content by artificial haemoglobin induces a decrease in regional cerebral blood flow and

Michael Schöler1, Christian Lenz, Wolfgang Kuschinsky

  • 1Clinic for Anesthesiology and Critical Care Medicine, Medical Faculty Mannheim, Germany.

European Journal of Anaesthesiology
|February 28, 2009
PubMed
Summary

High hemoglobin concentration reduced regional cerebral blood flow (CBF) in rats, even at normal hematocrit. This suggests that elevated hemoglobin can impair local oxygen delivery to specific brain regions.

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