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Transmitting Plant Viruses Using Whiteflies

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Published on: November 8, 2013

Reflections on the white plague.

Alimuddin Zumla¹, Peter Mwaba, Jim Huggett

¹Centre for Infectious Diseases and International Health, University College London Medical School, UCL Windeyer Institute of Medical Sciences, London, UK. a.zumla@ucl.ac.uk

The Lancet. Infectious Diseases

|February 28, 2009

Summary

This summary is machine-generated.

Tuberculosis remains a major global health threat, with drug-resistant strains and co-infections hindering control efforts. Increased investment in research offers hope, but past challenges necessitate continued vigilance.

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Area of Science:

Global Health
Infectious Diseases
Epidemiology

Background:

Tuberculosis (TB) is a leading cause of death globally, declared a global emergency by the World Health Organization (WHO) in 1993.
Despite effective treatments, TB has seen a resurgence, complicated by multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains.
The co-epidemics of TB and HIV/AIDS in sub-Saharan Africa have severely impacted national TB control programs.

Observation:

The international response to the 1993 WHO declaration of TB as a global emergency was initially insufficient.
The emergence of drug-resistant TB strains poses a significant challenge to global eradication efforts.
Sub-Saharan Africa faces a dual burden of TB and HIV/AIDS, exacerbating control program difficulties.

Findings:

Effective combination therapy for TB exists, yet disease resurgence and resistance patterns persist.
Recent increases in funding from agencies and governments signal a growing commitment to TB research.
The Stop TB Partnership has defined critical research priorities for TB control.

Implications:

Continued complacency is unwarranted despite renewed investment in TB research and control.
Addressing drug resistance and co-infections is crucial for effective global TB management.
Sustained and strategic investment is vital to overcome the persistent global TB burden.