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Updated: Jun 25, 2026

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
Published on: March 30, 2019
MicroRNAs as novel regulators of angiogenesis
Yajaira Suárez1, William C Sessa
1Vascular Biology and Therapuetics Program [corrected] Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Abstract:
MicroRNAs are short noncoding RNAs that function as negative regulators of gene expression. Posttranscriptional regulation by miRNAs is important for many aspects of development, homeostasis, and disease. Endothelial cells are key regulators of different aspects of vascular biology, including the formation of new blood vessels (angiogenesis). Here, we review the approaches and current experimental evidence for the involvement of miRNAs in the regulation of the angiogenic process and their potential therapeutic applications for vascular diseases associated with abnormal angiogenesis.
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