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Updated: Jun 25, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

Linear accelerator radiosurgery for cavernous sinus meningiomas.

Matthew M Kimball1, William A Friedman, Kelly D Foote

  • 1Department of Neurosurgery, University of Florida, Gainesville, FL 32610, USA.

Stereotactic and Functional Neurosurgery
|February 28, 2009
PubMed
Summary
This summary is machine-generated.

Linear accelerator (LINAC) radiosurgery offers excellent tumor control for cavernous sinus meningiomas, with a 10-year control rate of 98%. This treatment also shows a low rate of new neurological deficits, suggesting it is a safe and effective option.

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Area of Science:

  • Neurosurgery
  • Radiation Oncology

Background:

  • Cavernous sinus meningiomas are tumors that can cause significant neurological deficits.
  • Surgical resection of these tumors is associated with high morbidity.

Purpose of the Study:

  • To review the outcomes of linear accelerator (LINAC) radiosurgery for treating cavernous sinus meningiomas.
  • To evaluate tumor control and neurological function after LINAC radiosurgery.

Main Methods:

  • Retrospective analysis of 55 patients treated with LINAC radiosurgery.
  • Median follow-up of 50 months.
  • Evaluation of cranial nerve deficits, symptoms, and actuarial local tumor control.

Main Results:

  • Actuarial local tumor control was 100% at 5 years and 98% at 10 years.
  • 65% of patients showed improvement in cranial nerve deficits; 31% were unchanged.
  • Only one patient developed a new neurologic deficit.

Conclusions:

  • LINAC radiosurgery provides superior tumor control for cavernous sinus meningiomas compared to surgical resection.
  • This treatment modality demonstrates significantly lower morbidity rates.
  • This study represents the largest LINAC radiosurgery experience for these tumors to date.