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Updated: Jun 25, 2026

Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography
08:04

Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography

Published on: March 12, 2017

ECM macromolecules: rotary shadowing and transmission electron microscopy.

Michael J Sherratt1, Roger S Meadows, Helen K Graham

  • 1The University of Manchester, Oxford Road, Manchester, M13 9PT, UK. michael.j.sherratt@manchester.ac.uk

Methods in Molecular Biology (Clifton, N.J.)
|February 28, 2009
PubMed
Summary

Rotary shadowing electron microscopy uses heavy metal evaporation for high-resolution imaging of macromolecules. This technique is valuable for studying extracellular matrix components like collagens and glycoproteins.

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