Related Experiment Video
Updated: Jun 25, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Bioptics with LASIK flap first for the treatment of high ametropia
Merab L Dvali1, Nana A Tsinsadze, Bella V Sirbiladze
1Tbilisi State Medical University, Tbilisi, Georgia. modernoptics@hotmail.com
Purpose:
To report the safety and predictability of an alternate sequence of the bioptics procedure.
Methods:
In this prospective study of 50 eyes, phakic intraocular lenses (IOLs) and pseudophakic IOLs were implanted, followed by LASIK. The corneal flap was created, followed by lens implantation 3 days later. Laser ablation was performed to the stromal bed 3 months later. Fifty eyes with varying degrees of refractive error (range of manifest refraction spherical equivalent [MRSE], -19.50 to +8.50 diopters [D]) were treated. Follow-up ranged from 3 months to 4 years postoperatively.
Results:
No intra- or postoperative complications occurred. Postoperatively, MRSE ranged from -0.75 to +0.50 D. Mean residual refractive astigmatism ranged from +0.25 to +1.50 D postoperatively. Postoperative uncorrected visual acuity was 20/20 or better in 82% (41/50) of eyes and 20/40 or better in 98% (49/50) of eyes. No eyes experienced a loss of best spectacle-corrected visual acuity postoperatively.
Conclusions:
This modification of the sequence of procedures for bioptics provided safe and predictable outcomes.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Focusing of Light in the Eye
Ophthalmic Drug Delivery Systems
