Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 25, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Enhancing spinal fusion.

Edward C Benzel1, Lars Gilbertson, Robert A Mericle

  • 1Department of Neurosurgery, Center for Spine Health, Cleveland Clinic, Ohio, USA.

Clinical Neurosurgery
|March 3, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of an Expert Panel for Symptomatic Patients With Grade I Degenerative Lumbar Spondylolisthesis: A Randomized Clinical Trial.

Neurosurgery·2025
Same author

Automated Analysis of Surface Roughness and Waviness in Vertebral Bodies by Computed Tomography: Implications for Device Design in Spine Surgery.

World neurosurgery·2025
Same author

How Reliable is the Assessment of Fusion Status Following ACDF Using Dynamic Flexion-Extension Radiographs?

Global spine journal·2024
Same author

Preparing Residents to Navigate Neurosurgical Careers in the 21st Century: Implementation of a Yearlong Enhanced Didactics Curriculum.

World neurosurgery·2024
Same author

Patients May Return to Work Sooner After Laminoplasty: Occupational Outcomes of the Cervical Spondylotic Myelopathy Surgical Trial.

Neurosurgery·2024
Same author

Pedicle Subtraction Osteotomies for Surgical Correction of Fixed Sagittal Imbalance: A Meta-Analysis and Systematic Review.

Neurosurgery·2024

Optimizing bone healing parameters, including pressure and load, is crucial for improving bony fusion rates and patient outcomes. Further in vivo research in humans is needed to understand these factors for better surgical decision-making.

Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering
  • Bone Healing Research

Background:

  • Bony fusion is a complex orthopedic challenge impacting patient outcomes.
  • Current understanding of optimal bone healing conditions, particularly regarding mechanical loading, remains incomplete.
  • Wolff's Law suggests mechanical forces significantly influence bone adaptation and healing.

Purpose of the Study:

  • To highlight the importance of optimizing bone healing parameters for enhanced fusion rates.
  • To underscore the need for precise knowledge of loading conditions that promote bone healing.
  • To advocate for in vivo human studies to elucidate bone healing mechanisms.

Main Methods:

  • Review and discussion of existing knowledge on bone healing and mechanical influences.

Related Experiment Videos

Last Updated: Jun 25, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

  • Emphasis on the significance of pressure and load in the bone healing process.
  • Proposal for in vivo human measurements of mechanical parameters.

    • Main Results:

    • Optimizing bone healing enhancing parameters can improve fusion rates and patient outcomes.
    • The precise conditions (timing and load) for optimal bone healing are not yet fully understood.
    • Mechanical parameters like pressure and load are critical factors in bone healing.

    Conclusions:

    • Attention to the details of bone healing, particularly mechanical factors, is essential for surgical success.
    • In vivo measurement of pressure and load in humans will provide critical insights into bone healing.
    • Understanding and optimizing these parameters can positively influence bone healing and patient outcomes.