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Updated: Jun 25, 2026
10:47
Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs)
Published on: March 2, 2018
Clinical implications of current findings in neurodevelopment
Penelope Knapp1, Ann M Mastergeorge
1Department of Psychiatry and Behavioral Sciences, University of California, Davis, Medical Investigation of Neurodevelopmental Disorders Institute, Sacramento, CA 95817, USA. pkknapp@ucdavis.edu
The Psychiatric Clinics of North America
|March 3, 2009
Summary
Recent research highlights genetic and biological factors in childhood neurodevelopment. Advanced imaging techniques link early disorder signs to neurological changes, informing diagnosis and intervention.
Area of Science:
- Neuroscience
- Genetics
- Developmental Psychology
Background:
- Childhood neurodevelopment research has advanced significantly.
- Genetic research now includes epigenetics and gene-environment interactions.
- Biological vulnerability markers for disorders are being identified.
Purpose of the Study:
- To provide an overview of current neurodevelopmental findings.
- To discuss diagnostic factors, prevention, and intervention strategies.
- To explore clinical implications of recent research.
Main Methods:
- Review of genetic research, including epigenetics and gene-environment interactions.
- Analysis of biological markers for disorder vulnerability.
- Integration of findings from neuroimaging (EEG, ERP, fMRI) and other noninvasive techniques.
Main Results:
- Illumination of neuroanatomic region functions and interactions.
- Linking early disorder signs to specific neurological changes.
- Identification of biological and genetic factors influencing neurodevelopment.
Conclusions:
- Advances in understanding neurodevelopmental processes are substantial.
- New techniques enable early detection and linkage of disorders to neurological changes.
- Findings have significant implications for diagnosis, prevention, and intervention in childhood disorders.
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