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Related Concept Videos

Trachea01:22

Trachea

The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
The Bronchial Tree01:23

The Bronchial Tree

The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...

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Related Experiment Video

Updated: Jun 25, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
08:26

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis

Published on: January 21, 2020

Nonneoplastic tracheal and bronchial stenoses.

Philippe A Grenier1, Catherine Beigelman-Aubry, Pierre-Yves Brillet

  • 1Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Université Pierre et Marie Curie, 75651 Paris cedex 13, Paris, France. philippe.grenier@psl.aphp.fr

Radiologic Clinics of North America
|March 3, 2009
PubMed
Summary

Nonneoplastic airway stenosis, caused by various conditions, is now diagnosed earlier using CT imaging. Advanced CT techniques aid in assessing stenosis extent and guiding treatment for better patient outcomes.

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Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
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Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
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Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation

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Published on: January 21, 2020

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
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Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
06:15

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation

Published on: November 10, 2023

Area of Science:

  • Pulmonology
  • Radiology
  • Medical Imaging

Background:

  • Nonneoplastic stenosis of proximal airways can arise from prolonged intubation, infections, or systemic diseases.
  • Conditions like relapsing polychondritis, amyloidosis, and sarcoidosis are associated with airway stenosis.
  • Saber sheath trachea, tracheobronchopathia osteoplastica, and broncholithiasis are other potential causes.

Purpose of the Study:

  • To highlight the diagnostic capabilities of CT imaging for nonneoplastic airway stenosis.
  • To emphasize the role of advanced CT techniques in characterizing airway wall thickening.
  • To demonstrate how CT findings assist in procedural planning and treatment response assessment.

Main Methods:

  • Utilizing routine computed tomography (CT) imaging for early diagnosis.
  • Employing multiplanar and volume rendering reformations after thin collimation MDCT acquisition.
  • Analyzing airway wall thickening for presence, distribution, and type.

Main Results:

  • CT imaging enables early detection of tracheal and bronchial stenosis.
  • Advanced CT reformations accurately assess stenosis location and extent.
  • CT provides detailed characterization of airway wall abnormalities.

Conclusions:

  • CT imaging is crucial for the early diagnosis of nonneoplastic airway stenosis.
  • MDCT with advanced post-processing aids in comprehensive stenosis evaluation.
  • Radiological findings guide surgical and endoscopic interventions and treatment monitoring.