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Updated: Jun 25, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
Published on: January 21, 2020
Nonneoplastic tracheal and bronchial stenoses
Philippe A Grenier1, Catherine Beigelman-Aubry, Pierre-Yves Brillet
1Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Université Pierre et Marie Curie, 75651 Paris cedex 13, Paris, France. philippe.grenier@psl.aphp.fr
Abstract:
Nonneoplastic stenosis of proximal airways may result from longstanding intubations or tracheostomy, granulomatous infection, or systemic diseases such as relapsing polychondritis, amyloidosis, Wegener's granulomatosis, sarcoidosis, and inflammatory bowel disease. It also may be caused by saber sheath trachea, tracheobronchopathia osteoplastica, or broncholithiasis. An early diagnosis of the tracheal and bronchial stenosis has become possible with the advent of routine CT imaging. Multiplanar and volume rendering reformations after thin collimation MDCT acquisition help assess the location and extent of the stenosis and characterize the presence, distribution, and type of airway wall thickening. They also help surgeons and endoscopists to select adequate procedures and assess the response to treatment.
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