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Updated: Jun 25, 2026

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
Multidetector CT evaluation of tracheobronchomalacia
Edward Y Lee1, Diana Litmanovich, Phillip M Boiselle
1Department of Radiology and Medicine, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
Tracheobronchomalacia (TBM) is a growing cause of chronic respiratory issues. Dynamic expiratory multidetector CT (MDCT) offers accurate, noninvasive diagnosis, replacing older methods.
Area of Science:
- Pulmonology
- Radiology
- Medical Imaging
Background:
- Tracheobronchomalacia (TBM) involves excessive expiratory collapse of the trachea and bronchi due to weakened airway walls or cartilage.
- TBM is increasingly recognized as a significant cause of chronic respiratory symptoms.
Purpose of the Study:
- To highlight the role of multidetector CT (MDCT) in diagnosing Tracheobronchomalacia (TBM).
- To establish dynamic expiratory MDCT as the preferred imaging modality for suspected TBM.
Main Methods:
- Utilizes multidetector CT (MDCT) technology for noninvasive imaging.
- Employs paired end-inspiratory and dynamic expiratory scans.
- Compares MDCT accuracy to bronchoscopy, the historical reference standard.
Main Results:
- MDCT demonstrates similar accuracy to bronchoscopy for TBM diagnosis.
- Dynamic expiratory MDCT is identified as the examination of choice for TBM assessment.
Conclusions:
- Multidetector CT (MDCT) provides an accurate, noninvasive method for diagnosing Tracheobronchomalacia (TBM).
- Radiologists need to be proficient in MDCT protocols and interpretation for effective TBM diagnosis.
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